Monday, March 16, 2015

Anti-Cardiolipin (Anti-Phospholipid)

Anticardiolipin antibodies are a subset of a group of antibodies which react with negatively charged phospholipids. Antibodies to cardiolipin have been associated with an incresased incidence of vascular thrombosis, thrombocytopenia and recurrent fetal loss in patients with SLE.

Normal Range for anti-IgG: 0 - 20 GPL
Normal Range for anti-IgM: 0 - 10 MPL.

increased in: SLE, some connective tissue diseases, and in Antiphospholipid Syndrome.
Additional: Patients with acute and chronic infections (including syphilis, HIV, Lyme disease) may also have increased anti-cardiolipin antibodies
 

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